Distinct cellular and genetic differences in colorectal cancer in young patients

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Dana-Farber Cancer Institute researchers, along with Mass General Brigham researchers from the Gene Lay Institute of Immunology and Inflammation, and the Broad Institute, have uncovered biological clues to why colorectal cancer can behave more aggressively in younger people. Xavier, MD, PhD, of the Broad Institute, Mass General Brigham, and the Gene Lay Institute. Among tumors of the most common colorectal cancer subtype, younger patients’ tumors had a significantly higher proportion of connective and supporting cells relative to cancer cells.

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