Claude designed protein binders against scorpion neurotoxins

Automated excerpt

In de novo design, protein binders are generated from scratch against a specific target. But we were also curious if Claude could design binders that targeted multiple toxins. We later worked with Claude to add another 31 designs, increasing the total to 211 designs: 60 designs against a single toxin (12 per toxin), 30 designs against the two β-family toxins, 30 designs against the three α-family toxins, and 91 designs against all five toxins. Of the 211 designs our teams assessed, 17 met our criteria for a binder, each against a single toxin.

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