AI article

Why AI Isn’t Ready to Tackle Our Convoluted Genomes

Publisher description: The DNA inside our cells isn’t just a series of instructions, but something far more dynamic. Like scientists, AI models don't yet have the data to properly decode it.

Wired | Oct 17, 2026 | Philip Ball

Automated excerpt

In bacteria, transcription factors are rather like keys that fit the locks of unique binding sites on DNA. The compacted DNA there is relatively inaccessible to transcription factors; the genes it contains are typically silenced. While mRNA is produced from the protein-coding areas of DNA (so-called “coding genes”), noncoding RNAs are transcribed from other DNA regions now generally described as noncoding genes.

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