Tech article
Targeting ZMYND8 unleashes IL-2 signalling to override T cell exhaustion - Nature
Publisher description: ZMYND8 suppresses IL-2R–STAT5 signalling by inhibiting p300-mediated transcriptional activation of Il2ra to enforce CD8+ T cell terminal exhaustion, and its deletion boosts effector-like states and markedly enhances antiviral and antitumour imm…
NewsAPI | Sep 23, 2026 | Nature.com